Brand Name: Xalatan
Drug Class: Antiglaucoma
Available in: Ophthalmic
Available Without a Prescription? No
Available as a Generic? No
Serious: Chest pain,
difficulty breathing. Call your doctor right away.
vision, burning and stinging of the eye, sensation of something
the eye, increased brown pigmentation of the iris, eye redness.
Less Common: Dry
eye, excessive tearing, eye pain, lid crusting, swollen eyelid,
eyelid pain or discomfort, sensitivity to light, upper respiratory
double vision, pain in the chest and back.
To treat glaucoma.
How the Drug Works
Glaucoma, a sight-threatening disorder, occurs
when the aqueous humor (fluid inside the eye) cannot drain properly,
causing increased pressure within the eyeball (intraocular pressure).
Increased eye pressure can damage the optic nerve and lead to
a gradually progressive loss of vision. Latanoprost promotes
outflow of aqueous humor, thereby reducing intraocular pressure.
1 drop of latanoprost in each eye once daily in
Onset of Effect
3 to 4 hours.
Duration of Action
24 hours or more.
This medication can be used without regard to diet.
Store in a tightly sealed container away from heat,
moisture, and direct light. Do not allow the medicine to freeze.
If You Miss a Dose
Apply it as soon as you remember. If it is near
the time for the next dose, skip the missed dose and resume your
regular dosage schedule. Do not double the next dose.
Stopping the Drug
The decision to stop using the drug should be made
by your doctor.
See your doctor regularly for tests and examinations
if you must take this drug for a prolonged period.
Over 60: No special
problems are expected.
Driving and Hazardous Work: Do
not drive or engage in hazardous work until you determine how
the medicine affects your vision.
Alcohol: No special
precautions are necessary.
has not caused birth defects in animals. Human studies have not
been done. Before you take latanoprost, tell your doctor if you
are pregnant or plan to become pregnant.
Breast Feeding: Latanoprost
may pass into breast milk; caution is advised. Consult your doctor
Infants and Children: The
safety and effectiveness of latanoprost in infants and children
have not been established.
Special Concerns: To
use the eye drops, first wash your hands. Tilt your head back.
Gently apply pressure to the inside corner of the eyelid and
with the index finger of the same hand, pull downward on the
lower eyelid to make a space. Drop the medicine into this space
and close your eye. Apply pressure for 1 or 2 minutes while keeping
the eye closed without blinking. Then wash your hands again.
Make sure the tip of the dropper does not touch your eye, finger,
or any other surface. Latanoprost may make your eyes more sensitive
to sunlight. If this occurs, wear sunglasses or avoid exposure
to bright light as necessary. Latanoprost may change eye color,
increasing the brown pigment in the iris over a period of months
or years. The color change may be permanent. Latanoprost contains
ingredients that may damage contact lenses. Contact lenses should
be removed 15 minutes before applying the medication and reinserted
15 minutes or more afterward.
Symptoms: No specific
ones have been reported.
What to Do: An overdose
of latanoprost is unlikely to be life-threatening. If a large
volume enters the eyes, flush with water. If someone accidentally
ingests the medicine, call your doctor, emergency medical services
(EMS), or the nearest poison control center.
Other drugs may interact with latanoprost. Consult
your doctor for specific advice if you are taking any other prescription
or over-the-counter medication. If you are using other ophthalmic
medications to reduce fluid pressure in the eye, administer them
at least 5 minutes apart.
No known food interactions.
Use of latanoprost may cause complications in patients
with liver or kidney disease, since these organs work together
to remove the drug from the body.
From The Johns
Hopkins Consumer Guide to Drugs. You can order
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