Brand Name: Reminyl
Drug Class: Reversible
Available in: Tablets
Available OTC? No
As Generic? No
Serious: No serious
side effects are associated with the use of galantamine.
vomiting, diarrhea, loss of appetite, and weight loss.
Less Common: Fatigue,
lightheadedness, dizziness, tremor, headache, abdominal pain,
heartburn, depression, insomnia, drowsiness, runny nose, urinary
tract infection, blood
in the urine.
To treat mild to moderate Alzheimer disease.
How the Drug Works
The exact mechanism of action is unknown. However,
galantamine is believed to work by inhibiting acetylcholinesterase
enzymes, which reduces the breakdown of acetylcholine, a brain
chemical crucial to memory. Acetylcholine deficiency is thought
to result in memory loss associated with Alzheimer disease.
To start, 4 mg twice a day. After a minimum of
four weeks of treatment, your doctor may increase the dose to
8 mg twice a day. The dose may be further increased after no
less than a 4-week interval to 12 mg twice a day, if tolerated.
People with moderate liver or kidney impairment should not take
more than 16 mg a day.
Onset of Effect
Duration of Action
Rivastigmine should be taken with food in the morning
Store in a tightly sealed container away from
heat, moisture, and direct light.
If You Miss a Dose
Take it as soon as you remember. If it is near
the time for the next dose, skip the missed dose and resume your
regular dosage schedule. Do not double the next dose. If therapy
has been interrupted for several days or longer, consult your
Stopping the Drug
The decision to stop taking the drug should be
made in consultation with your physician.
No problems are expected with long-term use.
Over 60: No special
problems are expected.
Driving and Hazardous Work: Do
not drive or engage in hazardous work until you determine how
the medicine affects you.
Alcohol: Avoid alcohol
while using this medication.
studies on the use of galantamine during pregnancy have not been
done. Discuss with your doctor the relative risks and benefits
of using this drug while pregnant.
Breast Feeding: It
is not known whether galantamine passes into breast milk; caution
is advised. Consult your doctor for specific advice.
Infants and Children: Galantamine
is not intended for use in children.
Special Concerns: Galantamine
will not cure Alzheimer disease and will not stop the disease
from getting worse, but it will improve cognitive ability of
Symptoms: Severe nausea,
vomiting, increased salivation, sweating, slow heartbeat, low
blood pressure, irregular breathing, unconsciousness, increased
muscle weakness, death.
What to Do: Call your
doctor, emergency medical services (EMS), or the nearest poison
control center immediately.
The following drugs may interact with galantamine.
Consult your doctor for specific advice if you are taking anticholinergic
drugs or paroxetine.
No known food interactions.
Do not take galantamine if you have severe liver
or kidney impairment. Caution is advised when taking this drug.
Consult your doctor if you have any of the following: asthma,
obstructive pulmonary disease, epilepsy or a history of seizures,
heart problems, intestinal blockage, stomach or duodenal ulcer,
liver disease, or urinary problems.
From The Johns Hopkins Consumer Guide to Drugs. You
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