Brand Names: Aspergum,
Bayer Childrens, Bufferin, Easprin, Ecotrin, Empirin, Genprin,
Genuine Bayer, Halfprin, Magnaprin, ZORprin
Drug Class: Nonsteroidal
anti-inflammatory drug (NSAID); analgesic; anticoagulant
Available in: Tablets,
Available Without a Prescription? Yes
Available as a Generic? Yes
agitation, extreme fatigue, confusion; allergic reaction causing
troubled breathing, redness of face, itching,
swelling of face, lips, or
eyelids. These are symptoms of Reyes syndrome, a rare but serious
disorder that is most likely to affect people under the age of 16. Seek
medical attention immediately.
upset, rash, nausea, ringing in the ears.
Less Common: Insomnia
For mild to moderate everyday pain and inflammation;
to reduce fever; to prevent the formation of blood clots, a primary
cause of heart attack, stroke, and other circulatory problems;
to ease the inflammation, joint pain, and stiffness associated
How the Drug Works
Nonsteroidal anti-inflammatory drugs (NSAIDs) such
as aspirin inhibit the release of chemicals in the body called
prostaglandins, which play a role in inflammation, though it
is unknown exactly how they exert their pain-relieving, fever-reducing,
and anti-inflammatory effects.
For pain or fever: 325 to 650 mg every 4 hours
as needed. For prevention of blood clots: 80 to 100 mg daily
or every other day. For arthritis: 3,600 to 5,400 mg daily in
Onset of Effect
Duration of Action
For pain relief, up to 4 hours.
Swallow aspirin with food or a full glass of water
to lessen stomach irritation.
Store in a tightly sealed container away from heat
and direct light.
If You Miss a Dose
For pain and fever, take a missed dose as soon
as you remember, then wait 4 hours for your next dose. For arthritis,
take the aspirin as soon as you remember up to 2 hours late,
then return to your regular schedule.
Stopping the Drug
For pain and fever, stop when relief is achieved.
For arthritis and blood clotting, consult your doctor about stopping.
Talk to your doctor about the need for medical
examinations or laboratory tests if you must take aspirin regularly
for a prolonged period.
Over 60: Gastrointestinal
bleeding and irritation are more likely to occur in older persons.
Driving and Hazardous Work: The
use of aspirin should not impair your ability to perform such
Alcohol: Alcohol intake
should be limited because it increases the risk of stomach irritation
Pregnancy: Do not
use aspirin during the last 3 months of pregnancy unless prescribed
by your doctor.
Breast Feeding: Aspirin
passes into breast milk. Avoid it or do not nurse.
Infants and Children: Do
not give aspirin to children under age 16 unless your doctor
instructs otherwise, since it may cause a very rare but life-threatening
condition known as Reyes syndrome.
disorientation, seizures, vomiting, rapid breathing, fever.
What to Do: Call your
doctor, emergency medical services (EMS), or the nearest poison
control center immediately.
Consult your doctor before taking aspirin if you
currently take a blood pressure medication, a medication for
gout, an arthritis drug, an anticoagulant such as warfarin, a
diabetes medication, a steroid, or an antiseizure medication.
No known adverse food interactions. Taking aspirin
with caffeine-containing foods or beverages may actually enhance
the medicines pain-relieving effects.
Consult your doctor about taking aspirin if you
have asthma, a bleeding disorder, heart failure, diabetes, gout,
hemophilia, high blood pressure, kidney disease, liver disease,
thyroid disease, or a peptic ulcer.
From The Johns
Hopkins Consumer Guide to Drugs. You can order
this book now on our secure server.