Drug Class: Tricyclic
Available in: Tablets
Available OTC? No
As Generic? Yes
heartbeat (racing, pounding, or fluttering), confusion, seizures,
dry mouth, dizziness.
Less Common: Fatigue
or excessive tiredness, weakness, nausea, constipation, heartburn,
unpleasant bitter or metallic
taste in mouth, vision problems, headache, restlessness, nervousness,
difficulty urinating, unusual bleeding or bruising.
To relieve painful, temporary muscle stiffness
and spasms. It is not used for stiffness and spasms due to serious,
chronic illnesses of the nervous system and muscles, such as
spinal cord injury or cerebral palsy.
How the Drug Works
Cyclobenzaprine appears to work by decreasing nerve
impulses from the brain and spinal cord that lead to tensing
or tightening of muscle fibers.
Adults and teenagers 15 years of age and older:
Usual dose is 10 mg, 3 times a day, which may be increased by
your doctor to a maximum total dose of no more than 60 mg per
day. Children and teenagers up to 15 years of age: Consult pediatrician.
Onset of Effect
Within 1 hour. The maximum effect may require 1
to 2 weeks of therapy.
Duration of Action
12 to 24 hours following a single dose.
Dry mouth is a common complaint with muscle relaxants;
maintain adequate fluid intake and suck on ice chips if desired.
Store in a tightly sealed container away from heat
and direct light. Keep it away from moisture and extremes in
If You Miss a Dose
Take it as soon as you remember. If it is near
the time for the next dose, skip the missed dose and resume your
regular dosage schedule. Do not double the next dose.
Stopping the Drug
You should take it as prescribed for the full treatment
period, but you may stop if you are feeling better before the
scheduled end of therapy.
Therapy with cyclobenzaprine is usually completed
within 14 to 21 days. Do not take cyclobenzaprine for a longer
period without your doctor's approval. Muscle pain and stiffness
that does not improve within 14 to 21 days may require a more
Over 60: Adverse reactions
may be more likely and more severe in older patients.
Driving and Hazardous Work: The
use of cyclobenzaprine may impair your ability to perform such
tasks safely; use caution.
Alcohol: Avoid alcohol.
studies of cyclobenzaprine use during pregnancy have not been
done; discuss the relative risks and benefits with your doctor.
Breast Feeding: Cyclobenzaprine
may pass into breast milk; caution is advised. Consult your doctor
Infants and Children: Cyclobenzaprine
is not recommended for use by children under the age of 15.
Special Concerns: Cyclobenzaprine
is not meant to be used as the only treatment for sore or stiff
muscles. It should be accompanied by bed rest, physical therapy,
and other measures to relieve discomfort, such as the application
of heat or ice packs (as suggested by your physician).
Symptoms: Severe mental
confusion, agitation, impaired concentration, difficulty walking
or standing, dilated pupils, severe drowsiness, coma.
What to Do: Call emergency
medical services (EMS), your doctor, or the nearest poison control
Consult your doctor for
specific advice if you are taking sedatives, tranquilizers,
or other medications that cause drowsiness (including alcohol);
tricyclic antidepressants; or MAO inhibitors.
No known food interactions.
Consult your doctor if you have a history of any
of the following: glaucoma, difficult urination, prostate problems,
heart disease, or overactive thyroid.
From The Johns Hopkins Consumer Guide to Drugs. You
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